Cup holders Wigan Warriors, who beat Hull in last years final will travel to Kingston Press Championship side Dewsbury Rams.
The other notable ties is a West Yorkshire derby where Wakefield Wildcats will play Leeds Rhinos, Hull KR hosting Warrington Wolves, Salford Red Devils off to Hull FC and in France Catalan Dragons will play London Broncos.
The full draw below:-
Dewsbury Rams v Wigan Warriors
Wakefield Wildcats v Leeds Rhinos
Rochdale Hornets v Leigh Centurions
Batley Bulldogs v Castleford Tigers
Doncaster v Hemel Stags
Keighley Cougars v Barrow Raiders
Featherstone Rovers v North Wales Crusaders
Hull KR v Warrington Wolves
Hull FC v Salford Red Devils
Bradford Bulls v Oldham
Hunslet Hawks v Workington Town
Halifax v Widnes Vikings
Sheffield Eagles v London Skolars.
Swinton Lions v York City Knights
Ties to be played on the weekend of April 5 & 6